Patrick Dempsey juggles dual identities in thrilling drama ‘Memory of A Killer’

The first teaser for Fox's new psychological thriller, Memory Of A Killer, starring Patrick Dempsey and Michael Imperioli, has dropped.

The show is inspired by the 2003 Belgian film De Zaak Alzheimer (La Mémoire Du Tueur) and is expected to premiere in January 2026.

Dempsey plays Angelo Ledda, a professional hitman secretly struggling with early onset Alzheimer’s.

He leads two completely different lives, one as a feared killer in New York City, and another as a quiet family man and photocopier salesman in upstate Cooperstown.

But as his memory starts to fade, keeping those worlds apart becomes impossible.

As the official synopsis states, "Losing your memory is a devastating hammer blow for anyone but for Angelo Ledda, the stakes couldn’t be higher. His hitman job would be perilous enough, but there’s an added pressure. Angelo lives two totally separate lives as a fearsome NYC hitman and a sleepy upstate Cooperstown photocopier salesman and father."

“Having built and maintained a brick wall between his two worlds, Angelo has seamlessly juggled and compartmentalized for years. But now that’s all about to change. Because Alzheimer’s is a foe he can’t outrun, and he knows too well how this ends, as his older brother is already lost to the condition," the outline concludes.

The cast also includes Richard Harmon, Odeya Rush, Daniel David Stewart, Peter Gadiot and Gina Torres.

Fox’s president Michael Thorn described Patrick Dempsey's upcoming show as “a dramatic thriller with a noisy, unrelenting hook… one of the most emotionally charged stories I’ve seen in a long time.”