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Vitamin D linked to lower Alzheimer’s protein build-up, study finds
Findings showed that individuals with higher vitamin D levels tended to have fewer tangles of tau protein
New research suggests that higher levels of Vitamin D in midlife may be linked to lower buildup of harmful brain proteins associated with Alzheimer's disease.
In a study involving 793 adults, researchers analysed blood samples taken around age 39 and compared them with brain scans conducted roughly 16 years later.
The findings showed that individuals with higher vitamin D levels tended to have fewer tangles of tau protein, a key marker linked to Alzheimer’s.
Tau proteins are normally essential for brain function, but when they accumulate abnormally, they can disrupt communication between brain cells and contribute to cognitive decline.
While the study did not directly examine dementia diagnoses, these protein changes are considered early indicators of the disease.
Researchers found no significant link between vitamin D and another Alzheimer’s-related protein, amyloid-beta.
However, the association with tau was consistent across several brain regions typically affected in the early stages of the condition.
Scientists caution that the findings do not prove cause and effect and emphasize the need for further research, including long-term clinical trials.
Still, the results suggest that maintaining adequate vitamin D levels during midlife could play a role in reducing dementia risk.
Experts note that factors such as sunlight exposure and diet can influence vitamin D levels, but more evidence is needed before firm recommendations can be made.
