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Scientists link wheat bread to slower metabolism and increased fat storage

The findings point to metabolism, not just calories, as a key factor in weight gain

By GH Web Desk |
Scientists link wheat bread to slower metabolism and increased fat storage
Scientists link wheat bread to slower metabolism and increased fat storage

New research is shedding light on why bread and other carbohydrate-rich foods may contribute to weight gain even when overall calorie intake does not increase.

A study led by researchers at Osaka Metropolitan University found that diets high in wheat-based bread were linked to reduced energy expenditure and increased fat accumulation in laboratory mice, suggesting that metabolic changes not just calorie consumption, may play a key role in weight gain.

The findings challenge the conventional focus on calorie intake alone, pointing instead to how the body processes different types of food.

According to nutritionist Shigenobu Matsumura, the results indicate that weight gain may be driven less by wheat itself and more by a strong preference for carbohydrates and the metabolic shifts that follow.

To explore the link, researchers gave mice a choice between their regular cereal-based diet and alternative options, including wheat bread, baked wheat flour, and baked rice flour. 

The animals were then monitored for changes in body weight, fat mass, and how efficiently their bodies burned calories.

The study found that mice consistently gravitated toward carbohydrate-heavy options. 

Despite consuming similar amounts of calories, those on bread-based diets experienced increased weight gain and fat accumulation, particularly in male mice.

Further analysis revealed that these changes were not due to overeating or reduced activity levels. Instead, the diets appeared to lower overall energy expenditure while activating genes responsible for converting carbohydrates into fat.

Researchers also examined blood samples and liver tissue to assess hormone levels, blood sugar, and gene expression, providing deeper insight into how the body responds to high-carbohydrate diets at a biological level.

The findings suggest that certain foods may influence how the body stores fat and uses energy, highlighting the importance of metabolic responses, not just calorie counts, in understanding weight gain.